Thomas M. Wheeler, MD

Additional Publications

Koh H, Maru N, Muramoto M, Wheeler TM, Scardino PT, Ohori M "[The 1992 TNM classification of T2 prostate cancer predicts pathologic stage and prognosis better than the revised 1997 classification]." Nippon Hinyokika Gakkai Zasshi. 2002 July ; 93 (5): 595-601. Pubmed PMID: 12174634 

Shappell SB, Gupta RA, Manning S, Whitehead R, Boeglin WE, Schneider C, Case T, Price J, Jack GS, Wheeler TM, Matusik RJ, Brash AR, Dubois RN "15S-Hydroxyeicosatetraenoic acid activates peroxisome proliferator-activated receptor gamma and inhibits proliferation in PC3 prostate carcinoma cells.." Cancer Res.. 2001 January 15; 61 (2): 497-503. Pubmed PMID: 11212240 

Malins DC, Gilman NK, Green VM, Wheeler TM, Barker EA, Anderson KM "A cancer DNA phenotype in healthy prostates, conserved in tumors and adjacent normal cells, implies a relationship to carcinogenesis.." Proc. Natl. Acad. Sci. U.S.A.. 2005 December 27; 102 (52): 19093-6. Pubmed PMID: 16361440 

Ghetie V, Wheeler T, Scott D, Uhr JW, Vitetta ES "A CD4-derived peptide carrier blocks acute HIV-1 infection in vitro and binds to gp120 in the presence of Walter-Reed stage 1-6 HIV+ sera.." AIDS Res. Hum. Retroviruses. 1992 November ; 8 (11): 1945-8. Pubmed PMID: 1489581 

Greene DR, Wheeler TM, Egawa S, Dunn JK, Scardino PT "A comparison of the morphological features of cancer arising in the transition zone and in the peripheral zone of the prostate.." J. Urol.. 1991 October ; 146 (4): 1069-76. Pubmed PMID: 1895423 

Van Belle S, Swieboda-Sadlej A, Karanikiotis C, Labourey JL, Galid A, Wheeler T, Pujol B, Aerts JG "A final analysis from the CHOICE study examining darbepoetin alfa use for chemotherapy-induced anaemia in current European clinical practice.." Curr Med Res Opin. 2012 July ; 28 (7): 1079-87. Pubmed PMID: 22642867 

Evans PW, Wheeler T, Anthony FW, Osmond C "A longitudinal study of maternal serum vascular endothelial growth factor in early pregnancy.." Hum. Reprod.. 1998 April ; 13 (4): 1057-62. Pubmed PMID: 9619570 

Koh H, Kattan MW, Scardino PT, Suyama K, Maru N, Slawin K, Wheeler TM, Ohori M "A nomogram to predict seminal vesicle invasion by the extent and location of cancer in systematic biopsy results.." J. Urol.. 2003 October ; 170 (4): 1203-8. Pubmed PMID: 14501725 

O'Brien BA, Cohen RJ, Wheeler TM, Moorin RE "A post-radical-prostatectomy nomogram incorporating new pathological variables and interaction terms for improved prognosis.." BJU Int.. 2011 February ; 107 (3): 389-95. Pubmed PMID: 20707795 

Mikolajczyk SD, Millar LS, Wang TJ, Rittenhouse HG, Marks LS, Song W, Wheeler TM, Slawin KM "A precursor form of prostate-specific antigen is more highly elevated in prostate cancer compared with benign transition zone prostate tissue.." Cancer Res.. 2000 February 1; 60 (3): 756-9. Pubmed PMID: 10676664 

Amrikachi M, Ramzy I, Rubenfeld S, Wheeler TM "Accuracy of fine-needle aspiration of thyroid.." Arch. Pathol. Lab. Med.. 2001 April ; 125 (4): 484-8. Pubmed PMID: 11260620 

Truong LD, Ansari MQ, Ansari SJ, Wheeler TM, Mattioli CM, Gillum D "Acquired cystic kidney disease: occurrence in patients on chronic peritoneal dialysis.." Am. J. Kidney Dis.. 1988 February ; 11 (2): 192-5. Pubmed PMID: 3341377 

Sutton MA, Berkman SA, Chen SH, Block A, Dang TD, Kattan MW, Wheeler TM, Rowley DR, Woo SL, Lerner SP "Adenovirus-mediated suicide gene therapy for experimental bladder cancer.." Urology. 1997 February ; 49 (2): 173-80. Pubmed PMID: 9037277 

Kwabi-Addo B, Chung W, Shen L, Ittmann M, Wheeler T, Jelinek J, Issa JP "Age-related DNA methylation changes in normal human prostate tissues.." Clin. Cancer Res.. 2007 July 1; 13 (13): 3796-802. Pubmed PMID: 17606710 

Shappell SB, Manning S, Boeglin WE, Guan YF, Roberts RL, Davis L, Olson SJ, Jack GS, Coffey CS, Wheeler TM, Breyer MD, Brash AR "Alterations in lipoxygenase and cyclooxygenase-2 catalytic activity and mRNA expression in prostate carcinoma.." Neoplasia. 3 (4): 287-303. Pubmed PMID: 11571629 

Wolff AC, Hammond ME, Schwartz JN, Hagerty KL, Allred DC, Cote RJ, Dowsett M, Fitzgibbons PL, Hanna WM, Langer A, McShane LM, Paik S, Pegram MD, Perez EA, Press MF, Rhodes A, Sturgeon C, Taube SE, Tubbs R, Vance GH, van de Vijver M, Wheeler TM, Hayes DF "American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer.." J. Clin. Oncol.. 2007 January 1; 25 (1): 118-45. Pubmed PMID: 17159189 

Wolff AC, Hammond ME, Schwartz JN, Hagerty KL, Allred DC, Cote RJ, Dowsett M, Fitzgibbons PL, Hanna WM, Langer A, McShane LM, Paik S, Pegram MD, Perez EA, Press MF, Rhodes A, Sturgeon C, Taube SE, Tubbs R, Vance GH, van de Vijver M, Wheeler TM, Hayes DF "American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer.." Arch. Pathol. Lab. Med.. 2007 131 (1): 18-43. Pubmed PMID: 19548375 

Hammond ME, Hayes DF, Dowsett M, Allred DC, Hagerty KL, Badve S, Fitzgibbons PL, Francis G, Goldstein NS, Hayes M, Hicks DG, Lester S, Love R, Mangu PB, McShane L, Miller K, Osborne CK, Paik S, Perlmutter J, Rhodes A, Sasano H, Schwartz JN, Sweep FC, Taub "American society of clinical oncology/college of american pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer (unabridged version).." Arch. Pathol. Lab. Med.. 2010 July ; 134 (7): e48-72. Pubmed PMID: 20586616 

Hammond ME, Hayes DF, Dowsett M, Allred DC, Hagerty KL, Badve S, Fitzgibbons PL, Francis G, Goldstein NS, Hayes M, Hicks DG, Lester S, Love R, Mangu PB, McShane L, Miller K, Osborne CK, Paik S, Perlmutter J, Rhodes A, Sasano H, Schwartz JN, Sweep FC, Taub "American society of clinical oncology/college of american pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer.." Arch. Pathol. Lab. Med.. 2010 June ; 134 (6): 907-22. Pubmed PMID: 20524868 

Hammond ME, Hayes DF, Dowsett M, Allred DC, Hagerty KL, Badve S, Fitzgibbons PL, Francis G, Goldstein NS, Hayes M, Hicks DG, Lester S, Love R, Mangu PB, McShane L, Miller K, Osborne CK, Paik S, Perlmutter J, Rhodes A, Sasano H, Schwartz JN, Sweep FC, Taub "American society of clinical oncology/college of american pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer.." J. Clin. Oncol.. 2010 June 1; 28 (16): 2784-95. Pubmed PMID: 20404251 

Patel MI, DeConcini DT, Lopez-Corona E, Ohori M, Wheeler T, Scardino PT "An analysis of men with clinically localized prostate cancer who deferred definitive therapy.." J. Urol.. 2004 April ; 171 (4): 1520-4. Pubmed PMID: 15017211 

Cagiannos I, Graefen M, Karakiewicz PI, Ohori M, Eastham JA, Rabbani F, Fair W, Wheeler TM, Hammerer PG, Haese A, Erbersdobler A, Huland H, Scardino PT, Kattan MW "Analysis of clinical stage T2 prostate cancer: do current subclassifications represent an improvement?." J. Clin. Oncol.. 2002 April 15; 20 (8): 2025-30. Pubmed PMID: 11956261 

Wheeler T, Elcock CL, Anthony FW "Angiogenesis and the placental environment.." Placenta. 1995 April ; 16 (3): 289-96. Pubmed PMID: 7543674 

Rice L, Abramson SL, Laughter AH, Wheeler TM, Twomey JJ "Angioimmunoblastic lymphadenopathy with hypogammaglobulinemia. Possible role of monocyte suppression.." Am. J. Med.. 1982 June ; 72 (6): 998-1004. Pubmed PMID: 6211980 

McArthur WP, Bloom C, Taylor M, Smith J, Wheeler T, Magnusson NI "Antibody responses to suspected periodontal pathogens in elderly subjects with periodontal disease.." J. Clin. Periodontol.. 1995 November ; 22 (11): 842-9. Pubmed PMID: 8550860 

Lin WW, Lamb DJ, Wheeler TM, Abrams J, Lipshultz LI, Kim ED "Apoptotic frequency is increased in spermatogenic maturation arrest and hypospermatogenic states.." J. Urol.. 1997 November ; 158 (5): 1791-3. Pubmed PMID: 9334603 

Stapleton AM, Zbell P, Kattan MW, Yang G, Wheeler TM, Scardino PT, Thompson TC "Assessment of the biologic markers p53, Ki-67, and apoptotic index as predictive indicators of prostate carcinoma recurrence after surgery.." Cancer. 1998 January 1; 82 (1): 168-75. Pubmed PMID: 9428494

Eastham JA, Stapleton AM, Gousse AE, Timme TL, Yang G, Slawin KM, Wheeler TM, Scardino PT, Thompson TC "Association of p53 mutations with metastatic prostate cancer.." Clin. Cancer Res.. 1995 October ; 1 (10): 1111-8. Pubmed PMID: 9815901 

Shariat SF, Monoski MA, Andrews B, Wheeler TM, Lerner SP, Slawin KM "Association of plasma urokinase-type plasminogen activator and its receptor with clinical outcome in patients undergoing radical cystectomy for transitional cell carcinoma of the bladder.." Urology. 2003 May ; 61 (5): 1053-8. Pubmed PMID: 12736046 

Shariat SF, Kattan MW, Traxel E, Andrews B, Zhu K, Wheeler TM, Slawin KM "Association of pre- and postoperative plasma levels of transforming growth factor beta(1) and interleukin 6 and its soluble receptor with prostate cancer progression.." Clin. Cancer Res.. 2004 March 15; 10 (6): 1992-9. Pubmed PMID: 15041717 

Shariat SF, Lamb DJ, Kattan MW, Nguyen C, Kim J, Beck J, Wheeler TM, Slawin KM "Association of preoperative plasma levels of insulin-like growth factor I and insulin-like growth factor binding proteins-2 and -3 with prostate cancer invasion, progression, and metastasis.." J. Clin. Oncol.. 2002 February 1; 20 (3): 833-41. Pubmed PMID: 11821468 

Shariat SF, Anwuri VA, Lamb DJ, Shah NV, Wheeler TM, Slawin KM "Association of preoperative plasma levels of vascular endothelial growth factor and soluble vascular cell adhesion molecule-1 with lymph node status and biochemical progression after radical prostatectomy.." J. Clin. Oncol.. 2004 May 1; 22 (9): 1655-63. Pubmed PMID: 15117988 

Shariat SF, Roehrborn CG, McConnell JD, Park S, Alam N, Wheeler TM, Slawin KM "Association of the circulating levels of the urokinase system of plasminogen activation with the presence of prostate cancer and invasion, progression, and metastasis.." J. Clin. Oncol.. 2007 February 1; 25 (4): 349-55. Pubmed PMID: 17264329 

Kim ED, Nath R, Kadmon D, Lipshultz LI, Miles BJ, Slawin KM, Tang HY, Wheeler T, Scardino PT "Bilateral nerve graft during radical retropubic prostatectomy: 1-year followup.." J. Urol.. 2001 June ; 165 (6): 1950-6. Pubmed PMID: 11371887 

Li R, Wheeler TM, Dai H, Sayeeduddin M, Scardino PT, Frolov A, Ayala GE "Biological correlates of p27 compartmental expression in prostate cancer.." J. Urol.. 2006 February ; 175 (2): 528-32. Pubmed PMID: 16406988 

Ayala G, Satoh T, Li R, Shalev M, Gdor Y, Aguilar-Cordova E, Frolov A, Wheeler TM, Miles BJ, Rauen K, Teh BS, Butler EB, Thompson TC, Kadmon D "Biological response determinants in HSV-tk + ganciclovir gene therapy for prostate cancer.." Mol. Ther.. 2006 April ; 13 (4): 716-28. Pubmed PMID: 16480930 

Yossepowitch O, Sircar K, Scardino PT, Ohori M, Kattan MW, Wheeler TM, Reuter VE "Bladder neck involvement in pathological stage pT4 radical prostatectomy specimens is not an independent prognostic factor.." J. Urol.. 2002 November ; 168 (5): 2011-5. Pubmed PMID: 12394697 

Ayala G, Yan J, Li R, Ding Y, Thompson TC, Mims MP, Hayes TG, MacDonnell V, Lynch RG, Frolov A, Miles BJ, Wheeler TM, Harper JW, Tsai MJ, Ittmann MM, Kadmon D "Bortezomib-mediated inhibition of steroid receptor coactivator-3 degradation leads to activated Akt.." Clin. Cancer Res.. 2008 November 15; 14 (22): 7511-8. Pubmed PMID: 19010869 

Mikolajczyk SD, Millar LS, Wang TJ, Rittenhouse HG, Wolfert RL, Marks LS, Song W, Wheeler TM, Slawin KM. ""BPSA," a specific molecular form of free prostate-specific antigen, is found predominantly in the transition zone of patients with nodular benign prostatic hyperplasia.." Urology. 2000 January ; 55 (1): 41-5. Pubmed PMID: 10654892 

Ayala GE, Dai H, Li R, Ittmann M, Thompson TC, Rowley D, Wheeler TM "Bystin in perineural invasion of prostate cancer.." Prostate. 2006 February 15; 66 (3): 266-72. Pubmed PMID: 16245277 

Ohori M, Goad JR, Wheeler TM, Eastham JA, Thompson TC, Scardino PT "Can radical prostatectomy alter the progression of poorly differentiated prostate cancer?." J. Urol.. 1994 November ; 152 (5): 1843-9. Pubmed PMID: 7523732 

Hull GW, Rabbani F, Abbas F, Wheeler TM, Kattan MW, Scardino PT "Cancer control with radical prostatectomy alone in 1,000 consecutive patients.." J. Urol.. 2002 February ; 167 (2): 528-34. Pubmed PMID: 11792912 

Ayala GE, Dai H, Powell M, Li R, Ding Y, Wheeler TM, Shine D, Kadmon D, Thompson T, Miles BJ, Ittmann MM, Rowley D "Cancer-related axonogenesis and neurogenesis in prostate cancer.." Clin. Cancer Res.. 2008 December 1; 14 (23): 7593-603. Pubmed PMID: 19047084 

Malins DC, Johnson PM, Barker EA, Polissar NL, Wheeler TM, Anderson KM "Cancer-related changes in prostate DNA as men age and early identification of metastasis in primary prostate tumors.." Proc. Natl. Acad. Sci. U.S.A.. 2003 April 29; 100 (9): 5401-6. Pubmed PMID: 12702759 

Secin FP, Bianco FJ, Vickers AJ, Reuter V, Wheeler T, Fearn PA, Eastham JA, Scardino PT "Cancer-specific survival and predictors of prostate-specific antigen recurrence and survival in patients with seminal vesicle invasion after radical prostatectomy.." Cancer. 2006 June 1; 106 (11): 2369-75. Pubmed PMID: 16649221 

Yang G, Truong LD, Wheeler TM, Thompson TC "Caveolin-1 expression in clinically confined human prostate cancer: a novel prognostic marker.." Cancer Res.. 1999 November 15; 59 (22): 5719-23. Pubmed PMID: 10582690 

Kiniwa Y, Miyahara Y, Wang HY, Peng W, Peng G, Wheeler TM, Thompson TC, Old LJ, Wang RF "CD8+ Foxp3+ regulatory T cells mediate immunosuppression in prostate cancer.." Clin. Cancer Res.. 2007 December 1; 13 (23): 6947-58. Pubmed PMID: 18056169 

Cohen RJ, Shannon BA, Phillips M, Moorin RE, Wheeler TM, Garrett KL "Central zone carcinoma of the prostate gland: a distinct tumor type with poor prognostic features.." J. Urol.. 2008 May ; 179 (5): 1762-7; discuss. Pubmed PMID: 18343454 

Brophy B, Smolenski G, Wheeler T, Wells D, L'Huillier P, Laible G "Cloned transgenic cattle produce milk with higher levels of beta-casein and kappa-casein.." Nat. Biotechnol.. 2003 February ; 21 (2): 157-62. Pubmed PMID: 12548290 

Yang G, Stapleton AM, Wheeler TM, Truong LD, Timme TL, Scardino PT, Thompson TC "Clustered p53 immunostaining: a novel pattern associated with prostate cancer progression.." Clin. Cancer Res.. 1996 February ; 2 (2): 399-401. Pubmed PMID: 9816183 

Spittle MF, Bates TD, Kitchen G, Nicol NT, Wheeler T, Edelstyn G, MacRae KD, Ostrowski MJ "Combination chemotherapy in advanced breast cancer. A report of the Working Party of the Multicentre Cancer Chemotherapy Group.." Clin Oncol. 1980 June ; 6 (2): 153-7. Pubmed PMID: 7408282 

Yang G, Timme TL, Frolov A, Wheeler TM, Thompson TC "Combined c-Myc and caveolin-1 expression in human prostate carcinoma predicts prostate carcinoma progression.." Cancer. 2005 March 15; 103 (6): 1186-94. Pubmed PMID: 15712208 

Teh BS, Aguilar-Cordova E, Vlachaki MT, Aguilar L, Mai WY, Caillouet J, Davis M, Miles B, Kadmon D, Ayala G, Lu HH, Chiu JK, Carpenter LS, Woo SY, Grant WH, Wheeler T, Thompson TC, Butler EB "Combining radiotherapy with gene therapy (from the bench to the bedside): a novel treatment strategy for prostate cancer.." Oncologist. 2002 7 (5): 458-66. Pubmed PMID: 12401909 

Shariat SF, Roudier MP, Wilcox GE, Kattan MW, Scardino PT, Vessella RL, Erdamar S, Nguyen C, Wheeler TM, Slawin KM "Comparison of immunohistochemistry with reverse transcription-PCR for the detection of micrometastatic prostate cancer in lymph nodes.." Cancer Res.. 2003 August 1; 63 (15): 4662-70. Pubmed PMID: 12907647 

Ohori M, Wheeler TM, Greene DR, Scardino PT "Comparison of the pathologic features and DNA ploidy value of prostate cancers detectable by sonography and by palpation.." Prostate. 1993 23 (4): 271-81. Pubmed PMID: 8259341 

Shariat SF, Kim J, Nguyen C, Wheeler TM, Lerner SP, Slawin KM "Correlation of preoperative levels of IGF-I and IGFBP-3 with pathologic parameters and clinical outcome in patients with bladder cancer.." Urology. 2003 February ; 61 (2): 359-64. Pubmed PMID: 12597948 

Shariat SF, Bergamaschi F, Adler HL, Nguyen C, Kattan MW, Wheeler TM, Slawin KM "Correlation of preoperative plasma IGF-I levels with pathologic parameters and progression in patients undergoing radical prostatectomy.." Urology. 2000 September 1; 56 (3): 423-9. Pubmed PMID: 10962307 

Yang G, Addai J, Wheeler TM, Frolov A, Miles BJ, Kadmon D, Thompson TC "Correlative evidence that prostate cancer cell-derived caveolin-1 mediates angiogenesis.." Hum. Pathol.. 2007 November ; 38 (11): 1688-95. Pubmed PMID: 17707459 

Kattan MW, Eastham JA, Wheeler TM, Maru N, Scardino PT, Erbersdobler A, Graefen M, Huland H, Koh H, Shariat SF, Slawin KM, Ohori M "Counseling men with prostate cancer: a nomogram for predicting the presence of small, moderately differentiated, confined tumors.." J. Urol.. 2003 November ; 170 (5): 1792-7. Pubmed PMID: 14532778 

Bostwick DG, Montironi R, Nogle R, Pretlow T, Miller G, Wheeler T, Epstein J, Sakr W "Current and proposed biologic markers in prostate cancer.." J. Cell. Biochem. Suppl.. 1992 16 : 65-7. Pubmed PMID: 1289675 

Shariat SF, Kim JH, Ayala GE, Kho K, Wheeler TM, Lerner SP "Cyclooxygenase-2 is highly expressed in carcinoma in situ and T1 transitional cell carcinoma of the bladder.." J. Urol.. 2003 March ; 169 (3): 938-42. Pubmed PMID: 12576817 

Wu SL, Kothari P, Wheeler TM, Reese T, Connelly JH "Cytokeratins 7 and 20 immunoreactivity in chromophobe renal cell carcinomas and renal oncocytomas.." Mod. Pathol.. 2002 July ; 15 (7): 712-7. Pubmed PMID: 12118108 

Ayala G, Wheeler TM, Shalev M, Thompson TC, Miles B, Aguilar-Cordova E, Chakraborty S, Kadmon D "Cytopathic effect of in situ gene therapy in prostate cancer.." Hum. Pathol.. 2000 July ; 31 (7): 866-70. Pubmed PMID: 10923926 

Li R, Erdamar S, Dai H, Sayeeduddin M, Frolov A, Wheeler TM, Ayala GE "Cytoplasmic accumulation of glycogen synthase kinase-3beta is associated with aggressive clinicopathological features in human prostate cancer.." Anticancer Res.. 2009 June ; 29 (6): 2077-81. Pubmed PMID: 19528467 

Kench JG, Delahunt B, Griffiths DF, Humphrey PA, McGowan T, Trpkov K, Varma M, Wheeler TM, Srigley JR "Dataset for reporting of prostate carcinoma in radical prostatectomy specimens: recommendations from the International Collaboration on Cancer Reporting.." Histopathology. 2013 January ; 62 (2): 203-18. Pubmed PMID: 23240714 

Tokunaga H, Lee DH, Kim IY, Wheeler TM, Lerner SP "Decreased expression of transforming growth factor beta receptor type I is associated with poor prognosis in bladder transitional cell carcinoma patients.." Clin. Cancer Res.. 1999 September ; 5 (9): 2520-5. Pubmed PMID: 10499628 

McAlhany SJ, Ayala GE, Frolov A, Ressler SJ, Wheeler TM, Watson JE, Collins C, Rowley DR "Decreased stromal expression and increased epithelial expression of WFDC1/ps20 in prostate cancer is associated with reduced recurrence-free survival.." Prostate. 2004 October 1; 61 (2): 182-91. Pubmed PMID: 15305341 

Cohen RJ, O'Brien BA, Wheeler TM "Desquamating apoptotic variant of high-grade prostatic intraepithelial neoplasia: a possible precursor of intraductal prostatic carcinoma.." Hum. Pathol.. 2011 June ; 42 (6): 892-5. Pubmed PMID: 21288556 

Shariat SF, Kattan MW, Erdamar S, Nguyen C, Scardino PT, Spencer DM, Wheeler TM, Slawin KM "Detection of clinically significant, occult prostate cancer metastases in lymph nodes using a splice variant-specific rt-PCR assay for human glandular kallikrein.." J. Clin. Oncol.. 2003 April 1; 21 (7): 1223-31. Pubmed PMID: 12663708 

Slawin KM, Shariat SF, Nguyen C, Leventis AK, Song W, Kattan MW, Young CY, Tindall DJ, Wheeler TM "Detection of metastatic prostate cancer using a splice variant-specific reverse transcriptase-polymerase chain reaction assay for human glandular kallikrein.." Cancer Res.. 2000 December 15; 60 (24): 7142-8. Pubmed PMID: 11156423 

Ohori M, Egawa S, Shinohara K, Wheeler TM, Scardino PT "Detection of microscopic extracapsular extension prior to radical prostatectomy for clinically localized prostate cancer.." Br J Urol. 1994 July ; 74 (1): 72-9. Pubmed PMID: 7519116 

Egawa S, Wheeler TM, Greene DR, Scardino PT "Detection of residual prostate cancer after radiotherapy by sonographically guided needle biopsy.." Urology. 1992 April ; 39 (4): 358-63. Pubmed PMID: 1373015 

Ayala GE, Muezzinoglu B, Hammerich KH, Frolov A, Liu H, Scardino PT, Li R, Sayeeduddin M, Ittmann MM, Kadmon D, Miles BJ, Wheeler TM, Rowley DR "Determining Prostate Cancer-Specific Death through Quantification of Stromogenic Carcinoma Area in Prostatectomy Specimens.." Am. J. Pathol.. 2011 January ; 178 (1): 79-87. Pubmed PMID: 21224046 

Dietrich D, Hasinger O, Bañez LL, Sun L, van Leenders GJ, Wheeler TM, Bangma CH, Wernert N, Perner S, Freedland SJ, Corman JM, Ittmann MM, Lark AL, Madden JF, Hartmann A, Schatz P, Kristiansen G "Development and Clinical Validation of a Real-Time PCR Assay for PITX2 DNA Methylation to Predict Prostate-Specific Antigen Recurrence in Prostate Cancer Patients Following Radical Prostatectomy.." J Mol Diagn. 2013 March ; 15 (2): 270-9. Pubmed PMID: 23266319 

Tahir SA, Ren C, Timme TL, Gdor Y, Hoogeveen R, Morrisett JD, Frolov A, Ayala G, Wheeler TM, Thompson TC "Development of an immunoassay for serum caveolin-1: a novel biomarker for prostate cancer.." Clin. Cancer Res.. 2003 September 1; 9 (10): 3653-9. Pubmed PMID: 14506154 

Krouskop TA, Wheeler TM, Kallel F, Garra BS, Hall T "Elastic moduli of breast and prostate tissues under compression.." Ultrason Imaging. 1998 October ; 20 (4): 260-74. Pubmed PMID: 10197347 

Yang G, Addai J, Ittmann M, Wheeler TM, Thompson TC "Elevated caveolin-1 levels in African-American versus white-American prostate cancer.." Clin. Cancer Res.. 2000 September ; 6 (9): 3430-3. Pubmed PMID: 10999725 

Yang G, Truong LD, Timme TL, Ren C, Wheeler TM, Park SH, Nasu Y, Bangma CH, Kattan MW, Scardino PT, Thompson TC "Elevated expression of caveolin is associated with prostate and breast cancer.." Clin. Cancer Res.. 1998 August ; 4 (8): 1873-80. Pubmed PMID: 9717814 

Yang G, Ayala G, De Marzo A, Tian W, Frolov A, Wheeler TM, Thompson TC, Harper JW "Elevated Skp2 protein expression in human prostate cancer: association with loss of the cyclin-dependent kinase inhibitor p27 and PTEN and with reduced recurrence-free survival.." Clin. Cancer Res.. 2002 November ; 8 (11): 3419-26. Pubmed PMID: 12429629 

Truong LD, Harris L, Mattioli C, Hawkins E, Lee A, Wheeler T, Lane M "Endodermal sinus tumor of the mediastinum. A report of seven cases and review of the literature.." Cancer. 1986 August 1; 58 (3): 730-9. Pubmed PMID: 2425923 

Dai H, Li R, Wheeler T, Ozen M, Ittmann M, Anderson M, Wang Y, Rowley D, Younes M, Ayala GE "Enhanced survival in perineural invasion of pancreatic cancer: an in vitro approach.." Hum. Pathol.. 2007 February ; 38 (2): 299-307. Pubmed PMID: 17097719 

Satoh T, Teh BS, Timme TL, Mai WY, Gdor Y, Kusaka N, Fujita T, Pramudji CK, Vlachaki MT, Ayala G, Wheeler T, Amato R, Miles BJ, Kadmon D, Butler EB, Thompson TC "Enhanced systemic T-cell activation after in situ gene therapy with radiotherapy in prostate cancer patients.." Int. J. Radiat. Oncol. Biol. Phys.. 2004 June 1; 59 (2): 562-71. Pubmed PMID: 15145177 

Spitz MR, Strom SS, Yamamura Y, Troncoso P, Babaian RJ, Scardino PT, Wheeler T, Amos CI, von Eschenbach A, Kagan J "Epidemiologic determinants of clinically relevant prostate cancer.." Int. J. Cancer. 2000 May 20; 89 (3): 259-64. Pubmed PMID: 10861502 

Haqq C, Li R, Khodabakhsh D, Frolov A, Ginzinger D, Thompson T, Wheeler T, Carroll P, Ayala G "Ethnic and racial differences in prostate stromal estrogen receptor alpha.." Prostate. 2005 October 1; 65 (2): 101-9. Pubmed PMID: 15880569 

Kattan MW, Stapleton AM, Wheeler TM, Scardino PT "Evaluation of a nomogram used to predict the pathologic stage of clinically localized prostate carcinoma.." Cancer. 1997 February 1; 79 (3): 528-37. Pubmed PMID: 9028364

Aihara M, Truong LD, Dunn JK, Wheeler TM, Scardino PT, Thompson TC "Frequency of apoptotic bodies positively correlates with Gleason grade in prostate cancer.." Hum. Pathol.. 1994 August ; 25 (8): 797-801. Pubmed PMID: 7520020 

Rosen MA, Goldstone L, Lapin S, Wheeler T, Scardino PT "Frequency and location of extracapsular extension and positive surgical margins in radical prostatectomy specimens.." J. Urol.. 1992 August ; 148 (2): 331-7. Pubmed PMID: 1635129 

Eggener SE, Scardino PT, Carroll PR, Zelefsky MJ, Sartor O, Hricak H, Wheeler TM, Fine SW, Trachtenberg J, Rubin MA, Ohori M, Kuroiwa K, Rossignol M, Abenhaim L "Focal therapy for localized prostate cancer: a critical appraisal of rationale and modalities.." J. Urol.. 2007 December ; 178 (6): 2260-7. Pubmed PMID: 17936815 

Anton RC, Wheeler TM "Frozen section of thyroid and parathyroid specimens.." Arch. Pathol. Lab. Med.. 2005 December ; 129 (12): 1575-84. Pubmed PMID: 16329730 

Latour M, Amin MB, Billis A, Egevad L, Grignon DJ, Humphrey PA, Reuter VE, Sakr WA, Srigley JR, Wheeler TM, Yang XJ, Epstein JI "Grading of invasive cribriform carcinoma on prostate needle biopsy: an interobserver study among experts in genitourinary pathology.." Am. J. Surg. Pathol.. 2008 October ; 32 (10): 1532-9. Pubmed PMID: 18724248 

Rex JH, Harris RL, Wheeler T, White M, Bradshaw W, Williams TW "Granulomatous disease complicating hairy cell leukemia.." Tex Med. 1985 July ; 81 (7): 31-3. Pubmed PMID: 4035595 

Rice L, Shenkenberg T, Lynch EC, Wheeler TM "Granulomatous infections complicating hairy cell leukemia.." Cancer. 1982 May 1; 49 (9): 1924-8. Pubmed PMID: 7074589 

Ayala GE, Dai H, Ittmann M, Li R, Powell M, Frolov A, Wheeler TM, Thompson TC, Rowley D "Growth and survival mechanisms associated with perineural invasion in prostate cancer.." Cancer Res.. 2004 September 1; 64 (17): 6082-90. Pubmed PMID: 15342391 

Dillioglugil O, Leibman BD, Kattan MW, Seale-Hawkins C, Wheeler TM, Scardino PT "Hazard rates for progression after radical prostatectomy for clinically localized prostate cancer.." Urology. 1997 July ; 50 (1): 93-9. Pubmed PMID: 9218025 

Soh S, Kattan MW, Berkman S, Wheeler TM, Scardino PT "Has there been a recent shift in the pathological features and prognosis of patients treated with radical prostatectomy?." J. Urol.. 1997 June ; 157 (6): 2212-8. Pubmed PMID: 9146618 

Aihara M, Wheeler TM, Ohori M, Scardino PT "Heterogeneity of prostate cancer in radical prostatectomy specimens.." Urology. 1994 January ; 43 (1): 60-6; discussio. Pubmed PMID: 8284886 

Li R, Wheeler T, Dai H, Frolov A, Thompson T, Ayala G "High level of androgen receptor is associated with aggressive clinicopathologic features and decreased biochemical recurrence-free survival in prostate: cancer patients treated with radical prostatectomy.." Am. J. Surg. Pathol.. 2004 July ; 28 (7): 928-34. Pubmed PMID: 15223964 

Ayala G, Thompson T, Yang G, Frolov A, Li R, Scardino P, Ohori M, Wheeler T, Harper W "High levels of phosphorylated form of Akt-1 in prostate cancer and non-neoplastic prostate tissues are strong predictors of biochemical recurrence.." Clin. Cancer Res.. 2004 October 1; 10 (19): 6572-8. Pubmed PMID: 15475446 

Hall CA, Wang R, Miao J, Oliva E, Shen X, Wheeler T, Hilsenbeck SG, Orsulic S, Goode S "Hippo pathway effector yap is an ovarian cancer oncogene.." Cancer Res.. 2010 November 1; 70 (21): 8517-25. Pubmed PMID: 20947521 

Rogers E, Eastham JA, Ohori M, Sariyuce O, Aihara M, Wheeler TM, Scardino PT "Impalpable prostate cancer: clinicopathological features.." Br J Urol. 1996 March ; 77 (3): 429-32. Pubmed PMID: 8814851 

Cordon-Cardo C, Kotsianti A, Verbel DA, Teverovskiy M, Capodieci P, Hamann S, Jeffers Y, Clayton M, Elkhettabi F, Khan FM, Sapir M, Bayer-Zubek V, Vengrenyuk Y, Fogarsi S, Saidi O, Reuter VE, Scher HI, Kattan MW, Bianco FJ, Wheeler TM, Ayala GE, Scardino "Improved prediction of prostate cancer recurrence through systems pathology.." J. Clin. Invest.. 2007 July ; 117 (7): 1876-83. Pubmed PMID: 17557117 

Teh BS, Bastasch MD, Wheeler TM, Mai WY, Frolov A, Uhl BM, Lu HH, Carpenter LS, Chiu JK, McGary J, Woo SY, Grant WH, Butler EB "IMRT for prostate cancer: defining target volume based on correlated pathologic volume of disease.." Int. J. Radiat. Oncol. Biol. Phys.. 2003 May 1; 56 (1): 184-91. Pubmed PMID: 12694837 

Lin WW, Lamb DJ, Wheeler TM, Lipshultz LI, Kim ED "In situ end-labeling of human testicular tissue demonstrates increased apoptosis in conditions of abnormal spermatogenesis.." Fertil. Steril.. 1997 December ; 68 (6): 1065-9. Pubmed PMID: 9418698 

Thompson TC, Timme TL, Ebara S, Satoh T, Yang G, Wang J, Miles BJ, Ayala G, Wheeler TM, Kadmon D "In situ gene therapy for prostate cancer: immunomodulatory approaches.." Expert Opin Biol Ther. 2001 May ; 1 (3): 481-95. Pubmed PMID: 11727520 

Ayala GE, Wheeler TM, Shine HD, Schmelz M, Frolov A, Chakraborty S, Rowley D "In vitro dorsal root ganglia and human prostate cell line interaction: redefining perineural invasion in prostate cancer.." Prostate. 2001 November 1; 49 (3): 213-23. Pubmed PMID: 11746267 

Sutton MA, Freund CT, Berkman SA, Dang TD, Kattan MW, Wheeler TM, Rowley DR, Lerner SP "In vivo adenovirus-mediated suicide gene therapy of orthotopic bladder cancer.." Mol. Ther.. 2000 September ; 2 (3): 211-7. Pubmed PMID: 10985951 

Kothari PS, Scardino PT, Ohori M, Kattan MW, Wheeler TM "Incidence, location, and significance of periprostatic and periseminal vesicle lymph nodes in prostate cancer.." Am. J. Surg. Pathol.. 2001 November ; 25 (11): 1429-32. Pubmed PMID: 11684961 

Stepanova L, Yang G, DeMayo F, Wheeler TM, Finegold M, Thompson TC, Harper JW "Induction of human Cdc37 in prostate cancer correlates with the ability of targeted Cdc37 expression to promote prostatic hyperplasia.." Oncogene. 2000 April 27; 19 (18): 2186-93. Pubmed PMID: 10822368 

Taylor CM, Stevens H, Anthony FW, Wheeler T "Influence of hypoxia on vascular endothelial growth factor and chorionic gonadotrophin production in the trophoblast-derived cell lines: JEG, JAr and BeWo.." Placenta. 18 (41400): 451-8. Pubmed PMID: 9250709 

DeFrancisco AL, Macdougall IC, Carrera F, Braun J, Bárány P, Bridges I, Wheeler T, Tran D, Dietrich A "Intercurrent events and comorbid conditions influence hemoglobin level variability in dialysis patients.." Clin. Nephrol.. 2009 April ; 71 (4): 397-404. Pubmed PMID: 19356372 

Magi-Galluzzi C, Evans AJ, Delahunt B, Epstein JI, Griffiths DF, van der Kwast TH, Montironi R, Wheeler TM, Srigley JR, Egevad LL, Humphrey PA "International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 3: extraprostatic extension, lymphovascular invasion and locally advanced disease.." Mod. Pathol.. 2011 January ; 24 (1): 26-38. Pubmed PMID: 20802467 

Berney DM, Wheeler TM, Grignon DJ, Epstein JI, Griffiths DF, Humphrey PA, van der Kwast T, Montironi R, Delahunt B, Egevad L, Srigley JR "International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 4: seminal vesicles and lymph nodes.." Mod. Pathol.. 2011 January ; 24 (1): 39-47. Pubmed PMID: 20818343 

Samaratunga H, Montironi R, True L, Epstein JI, Griffiths DF, Humphrey PA, van der Kwast T, Wheeler TM, Srigley JR, Delahunt B, Egevad L "International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 1: specimen handling.." Mod. Pathol.. 2011 January ; 24 (1): 41440. Pubmed PMID: 20834234 

Tan PH, Cheng L, Srigley JR, Griffiths D, Humphrey PA, van der Kwast TH, Montironi R, Wheeler TM, Delahunt B, Egevad L, Epstein JI "International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 5: surgical margins.." Mod. Pathol.. 2011 January ; 24 (1): 48-57. Pubmed PMID: 20729812 

Epstein JI, Grignon DJ, Humphrey PA, McNeal JE, Sesterhenn IA, Troncoso P, Wheeler TM "Interobserver reproducibility in the diagnosis of prostatic intraepithelial neoplasia.." Am. J. Surg. Pathol.. 1995 August ; 19 (8): 873-86. Pubmed PMID: 7611534 

Allsbrook WC, Mangold KA, Johnson MH, Lane RB, Lane CG, Amin MB, Bostwick DG, Humphrey PA, Jones EC, Reuter VE, Sakr W, Sesterhenn IA, Troncoso P, Wheeler TM, Epstein JI "Interobserver reproducibility of Gleason grading of prostatic carcinoma: urologic pathologists.." Hum. Pathol.. 2001 January ; 32 (1): 74-80. Pubmed PMID: 11172298 

Kim ED, Scardino PT, Hampel O, Mills NL, Wheeler TM, Nath RK "Interposition of sural nerve restores function of cavernous nerves resected during radical prostatectomy.." J. Urol.. 1999 January ; 161 (1): 188-92. Pubmed PMID: 10037395 

Bonkhoff H, Wheeler TM, van der Kwast TH, Magi-Galluzzi C, Montironi R, Cohen RJ "Intraductal carcinoma of the prostate: Precursor or aggressive phenotype of prostate cancer?." Prostate. 2013 March ; 73 (4): 442-8. Pubmed PMID: 22949099 

Adler HL, Haddad JL, Wheeler TM, Kim ED "Intratesticular adenomatoid tumor radiographically mimicking a primary testicular malignancy.." ScientificWorldJournal. 2004 June 7; 4 : 41583. Pubmed PMID: 15349521 

Font RL, Wheeler TM, Boniuk M "Intravascular papillary endothelial hyperplasia of the orbit and ocular adnexa. A report of five cases.." Arch. Ophthalmol.. 1983 November ; 101 (11): 1731-6. Pubmed PMID: 6685471 

Kikuchi E, Scardino PT, Wheeler TM, Slawin KM, Ohori M "Is tumor volume an independent prognostic factor in clinically localized prostate cancer?." J. Urol.. 2004 August ; 172 (2): 508-11. Pubmed PMID: 15247716 

Cagiannos I, Karakiewicz P, Graefen M, Eastham JA, Ohori M, Rabbani F, Reuter V, Wheeler T, Kupelian P, Klein E, Huland H, Hammerer PG, Erbersdobler A, Schroeder F, Wildhagen M, Quinn DI, Henshall SM, Grygiel JJ, Sutherland RL, Stricker PD, Morash CG, Sca "Is year of radical prostatectomy a predictor of outcome in prostate cancer?." J. Urol.. 2004 February ; 171 (2): 692-6. Pubmed PMID: 14713788 

Goldfarb R, Pool JL, Wheeler T "Isolated renal artery dissection secondary to medial degeneration.." J. Urol.. 1988 February ; 139 (2): 346-7. Pubmed PMID: 3339739 

Panko WB, Mattioli CA, Wheeler TM "Lack of correlation of a histochemical method for estrogen receptors analysis with the biochemical assay results.." Cancer. 1982 May 15; 49 (10): 2148-52. Pubmed PMID: 7074530 

Chang S, Hursting SD, Contois JH, Strom SS, Yamamura Y, Babaian RJ, Troncoso P, Scardino PS, Wheeler TM, Amos CI, Spitz MR "Leptin and prostate cancer.." Prostate. 2001 January 1; 46 (1): 62-7. Pubmed PMID: 11170133 

Ostrowski ML, Brown RW, Wheeler TM, Green LK, Schaffner DL "Leu-7 immunoreactivity in cytologic specimens of thyroid lesions, with emphasis on follicular neoplasms.." Diagn. Cytopathol.. 1995 June ; 12 (4): 297-302. Pubmed PMID: 7544717 

Erdamar S, Yang G, Harper JW, Lu X, Kattan MW, Thompson TC, Wheeler TM "Levels of expression of p27KIP1 protein in human prostate and prostate cancer: an immunohistochemical analysis.." Mod. Pathol.. 1999 August ; 12 (8): 751-5. Pubmed PMID: 10463475 

Hammerich KH, Hille S, Ayala GE, Wheeler TM, Engers R, Ackermann R, Mueller-Mattheis V "Malignant advanced granulosa cell tumor of the adult testis: case report and review of the literature.." Hum. Pathol.. 2008 May ; 39 (5): 701-9. Pubmed PMID: 18304605 

Teh BS, Ayala G, Aguilar L, Mai WY, Timme TL, Vlachaki MT, Miles B, Kadmon D, Wheeler T, Caillouet J, Davis M, Carpenter LS, Lu HH, Chiu JK, Woo SY, Thompson T, Aguilar-Cordova E, Butler EB "Phase I-II trial evaluating combined intensity-modulated radiotherapy and in situ gene therapy with or without hormonal therapy in treatment of prostate cancer-interim report on PSA response and biopsy data.." Int. J. Radiat. Oncol. Biol. Phys.. 2004 April 1; 58 (5): 1520-9. Pubmed PMID: 15050332 

Teh BS, Aguilar-Cordova E, Kernen K, Chou CC, Shalev M, Vlachaki MT, Miles B, Kadmon D, Mai WY, Caillouet J, Davis M, Ayala G, Wheeler T, Brady J, Carpenter LS, Lu HH, Chiu JK, Woo SY, Thompson T, Butler EB "Phase I/II trial evaluating combined radiotherapy and in situ gene therapy with or without hormonal therapy in the treatment of prostate cancer--a preliminary report.." Int. J. Radiat. Oncol. Biol. Phys.. 2001 November 1; 51 (3): 605-13. Pubmed PMID: 11597799 

Dai H, Li R, Wheeler T, Diaz de Vivar A, Frolov A, Tahir S, Agoulnik I, Thompson T, Rowley D, Ayala G "Pim-2 upregulation: biological implications associated with disease progression and perinueral invasion in prostate cancer.." Prostate. 2005 November 1; 65 (3): 276-86. Pubmed PMID: 16015593 

Shariat SF, Andrews B, Kattan MW, Kim J, Wheeler TM, Slawin KM "Plasma levels of interleukin-6 and its soluble receptor are associated with prostate cancer progression and metastasis.." Urology. 2001 December ; 58 (6): 1008-15. Pubmed PMID: 11744478 

Singh H, Canto EI, Shariat SF, Kadmon D, Miles BJ, Wheeler TM, Slawin KM "Predictors of prostate cancer after initial negative systematic 12 core biopsy.." J. Urol.. 2004 May ; 171 (5): 1850-4. Pubmed PMID: 15076292 

Kim JH, Shariat SF, Kim IY, Menesses-Diaz A, Tokunaga H, Wheeler TM, Lerner SP "Predictive value of expression of transforming growth factor-beta(1) and its receptors in transitional cell carcinoma of the urinary bladder.." Cancer. 2001 September 15; 92 (6): 1475-83. Pubmed PMID: 11745225 

Leventis AK, Shariat SF, Kattan MW, Butler EB, Wheeler TM, Slawin KM "Prediction of response to salvage radiation therapy in patients with prostate cancer recurrence after radical prostatectomy.." J. Clin. Oncol.. 2001 February 15; 19 (4): 1030-9. Pubmed PMID: 11181666 

Tahir SA, Frolov A, Hayes TG, Mims MP, Miles BJ, Lerner SP, Wheeler TM, Ayala G, Thompson TC, Kadmon D "Preoperative serum caveolin-1 as a prognostic marker for recurrence in a radical prostatectomy cohort.." Clin. Cancer Res.. 2006 August 15; 12 (16): 4872-5. Pubmed PMID: 16914574 

Iczkowski KA, Hossain D, Torkko KC, Qian J, Lucia MS, Wheeler TM, Rewcastle JC, Bostwick DG "Preoperative prediction of unifocal, unilateral, margin-negative, and small volume prostate cancer.." Urology. 2008 June ; 71 (6): 1166-71. Pubmed PMID: 18279927 

Matsumoto K, Shariat SF, Casella R, Wheeler TM, Slawin KM, Lerner SP "Preoperative plasma soluble E-cadherin predicts metastases to lymph nodes and prognosis in patients undergoing radical cystectomy.." J. Urol.. 2003 December ; 170 (6): 2248-52. Pubmed PMID: 14634390 

Stapleton AM, Timme TL, Gousse AE, Li QF, Tobon AA, Kattan MW, Slawin KM, Wheeler TM, Scardino PT, Thompson TC "Primary human prostate cancer cells harboring p53 mutations are clonally expanded in metastases.." Clin. Cancer Res.. 1997 August ; 3 (8): 1389-97. Pubmed PMID: 9815823

Eastham JA, Kuroiwa K, Ohori M, Serio AM, Gorbonos A, Maru N, Vickers AJ, Slawin KM, Wheeler TM, Reuter VE, Scardino PT "Prognostic significance of location of positive margins in radical prostatectomy specimens.." Urology. 2007 November ; 70 (5): 965-9. Pubmed PMID: 18068455 

Ohori M, Wheeler TM, Kattan MW, Goto Y, Scardino PT "Prognostic significance of positive surgical margins in radical prostatectomy specimens.." J. Urol.. 1995 November ; 154 (5): 1818-24. Pubmed PMID: 7563355 

Li R, Dai H, Wheeler TM, Sayeeduddin M, Scardino PT, Frolov A, Ayala GE "Prognostic value of Akt-1 in human prostate cancer: a computerized quantitative assessment with quantum dot technology.." Clin. Cancer Res.. 2009 May 15; 15 (10): 3568-73. Pubmed PMID: 19417030 

Shariat SF, Weizer AZ, Green A, Laucirica R, Frolov A, Wheeler TM, Lerner SP "Prognostic value of P53 nuclear accumulation and histopathologic features in T1 transitional cell carcinoma of the urinary bladder.." Urology. 2000 November 1; 56 (5): 735-40. Pubmed PMID: 11068290 

Lopez-Corona E, Ohori M, Wheeler TM, Reuter VE, Scardino PT, Kattan MW, Eastham JA "Prostate cancer diagnosed after repeat biopsies have a favorable pathological outcome but similar recurrence rate.." J. Urol.. 2006 March ; 175 (3): 923-7; discussi. Pubmed PMID: 16469581 

Weinreb JC, Blume JD, Coakley FV, Wheeler TM, Cormack JB, Sotto CK, Cho H, Kawashima A, Tempany-Afdhal CM, Macura KJ, Rosen M, Gerst SR, Kurhanewicz J "Prostate cancer: sextant localization at MR imaging and MR spectroscopic imaging before prostatectomy--results of ACRIN prospective multi-institutional clinicopathologic study.." Radiology. 2009 April ; 251 (1): 122-33. Pubmed PMID: 19332850 

Aihara M, Lebovitz RM, Wheeler TM, Kinner BM, Ohori M, Scardino PT "Prostate specific antigen and gleason grade: an immunohistochemical study of prostate cancer.." J. Urol.. 1994 June ; 151 (6): 1558-64. Pubmed PMID: 7514688 

Miles BJ, Shalev M, Aguilar-Cordova E, Timme TL, Lee HM, Yang G, Adler HL, Kernen K, Pramudji CK, Satoh T, Gdor Y, Ren C, Ayala G, Wheeler TM, Butler EB, Kadmon D, Thompson TC "Prostate-specific antigen response and systemic T cell activation after in situ gene therapy in prostate cancer patients failing radiotherapy.." Hum. Gene Ther.. 2001 November 1; 12 (16): 1955-67. Pubmed PMID: 11686937 

Scardino PT, Wheeler TM "Prostatic biopsy after irradiation therapy for prostatic cancer.." Urology. 1985 February ; 25 (2): 39-46. Pubmed PMID: 3918375 

Shen SS, Lerner SP, Muezzinoglu B, Truong LD, Amiel G, Wheeler TM "Prostatic involvement by transitional cell carcinoma in patients with bladder cancer and its prognostic significance.." Hum. Pathol.. 2006 June ; 37 (6): 726-34. Pubmed PMID: 16733214 

Iczkowski KA, Torkko KC, Kotnis GR, Wilson RS, Huang W, Wheeler TM, Abeyta AM, Lucia MS "Pseudolumen size and perimeter in prostate cancer: correlation with patient outcome.." Prostate Cancer. 2011 2011 : 693853. Pubmed PMID: 22110997

Ayala G, Tuxhorn JA, Wheeler TM, Frolov A, Scardino PT, Ohori M, Wheeler M, Spitler J, Rowley DR "Reactive stroma as a predictor of biochemical-free recurrence in prostate cancer.." Clin. Cancer Res.. 2003 October 15; 9 (13): 4792-801. Pubmed PMID: 14581350 

Rogers E, Ohori M, Kassabian VS, Wheeler TM, Scardino PT "Salvage radical prostatectomy: outcome measured by serum prostate specific antigen levels.." J. Urol.. 1995 January ; 153 (1): 104-10. Pubmed PMID: 7526002 

Neerhut GJ, Wheeler T, Cantini M, Scardino PT "Salvage radical prostatectomy for radiorecurrent adenocarcinoma of the prostate.." J. Urol.. 1988 September ; 140 (3): 544-9. Pubmed PMID: 3411670 

Wheeler T "Second opinions in pathology.." J. Urol.. 2010 March ; 183 (3): 850-1. Pubmed PMID: 20089265 

Ishii J, Ohori M, Scardino P, Tsuboi T, Slawin K, Wheeler T "Significance of the craniocaudal distribution of cancer in radical prostatectomy specimens.." Int. J. Urol.. 2007 September ; 14 (9): 817-21. Pubmed PMID: 17760748 

Singh H, Canto EI, Shariat SF, Kadmon D, Miles BJ, Wheeler TM, Slawin KM "Six additional systematic lateral cores enhance sextant biopsy prediction of pathological features at radical prostatectomy.." J. Urol.. 2004 January ; 171 (1): 204-9. Pubmed PMID: 14665877 

Burch D, Metcalfe S, Gallagher G, al-Azzawi F, Wheeler T "Soluble interleukin-2 receptors and CA 125 in ovarian cancer, a longitudinal and cross-sectional study.." Eur. J. Gynaecol. Oncol.. 1994 15 (5): 352-8. Pubmed PMID: 7828604 

Gilcrease MZ, Schmidt L, Zbar B, Truong L, Rutledge M, Wheeler TM "Somatic von Hippel-Lindau mutation in clear cell papillary cystadenoma of the epididymis.." Hum. Pathol.. 1995 December ; 26 (12): 1341-6. Pubmed PMID: 8522307 

Greene DR, Rogers E, Wessels EC, Wheeler TM, Taylor SR, Santucci RA, Thompson TC, Scardino PT "Some small prostate cancers are nondiploid by nuclear image analysis: correlation of deoxyribonucleic acid ploidy status and pathological features.." J. Urol.. 1994 May ; 151 (5): 1301-7. Pubmed PMID: 8158775 

Egawa S, Carter SS, Wheeler TM, Scardino PT "Sonographic monitoring of prostate cancer after definitive radiotherapy.." Urology. 1992 September ; 40 (3): 230-6. Pubmed PMID: 1523746 

Sakr WA, Wheeler TM, Blute M, Bodo M, Calle-Rodrigue R, Henson DE, Mostofi FK, Seiffert J, Wojno K, Zincke H "Staging and reporting of prostate cancer--sampling of the radical prostatectomy specimen.." Cancer. 1996 July 15; 78 (2): 366-8. Pubmed PMID: 8674019 

Scardino PT, Shinohara K, Wheeler TM, Carter SS "Staging of prostate cancer. Value of ultrasonography.." Urol. Clin. North Am.. 1989 November ; 16 (4): 713-34. Pubmed PMID: 2683301 

Yanagisawa N, Li R, Rowley D, Liu H, Kadmon D, Miles BJ, Wheeler TM, Ayala GE "Stromogenic prostatic carcinoma pattern (carcinomas with reactive stromal grade 3) in needle biopsies predicts biochemical recurrence-free survival in patients after radical prostatectomy.." Hum. Pathol.. 2007 November ; 38 (11): 1611-20. Pubmed PMID: 17868773 

Harris RL, Lawrie GM, Wheeler TM, Rex JH, Sarosi GA, Jacob MC, Bradshaw MW, Williams TW "Successful management of Histoplasma capsulatum infection of an abdominal aortic aneurysm.." J. Vasc. Surg.. 1986 April ; 3 (4): 649-51. Pubmed PMID: 3959262 

Slawin KM, Canto EI, Shariat SF, Gore JL, Kim E, Kattan MW, Wheeler TM, Nath RK "Sural Nerve Interposition Grafting during Radical Prostatectomy.." Rev Urol. 2002 4 (1): 17-23. Pubmed PMID: 16985648 

McGuire AL, Majumder MA, Halpern SD, Swindell JS, Yaeger LV, Gibbs RA, Wheeler TM "Taking DNA from the dead.." Nat. Rev. Genet.. 2010 May ; 11 (5): 318. Pubmed PMID: 20332774 

Truong LD, Ostrowski ML, Wheeler TM "Tamm-Horsfall protein in bladder tissue. Morphologic spectrum and clinical significance.." Am. J. Surg. Pathol.. 1994 June ; 18 (6): 615-22. Pubmed PMID: 8179076 

Meacham RB, Mata JA, Espada R, Wheeler TM, Schum CW, Scardino PT "Testicular metastasis as the first manifestation of colon carcinoma.." J. Urol.. 1988 September ; 140 (3): 621-2. Pubmed PMID: 3411689 

Coburn M, Wheeler T, Lipshultz LI "Testicular biopsy. Its use and limitations.." Urol. Clin. North Am.. 1987 August ; 14 (3): 551-61. Pubmed PMID: 3617269 

Shinohara K, Wheeler TM, Scardino PT "The appearance of prostate cancer on transrectal ultrasonography: correlation of imaging and pathological examinations.." J. Urol.. 1989 July ; 142 (1): 76-82. Pubmed PMID: 2659828 

Hu JC, Palapattu GS, Kattan MW, Scardino PT, Wheeler TM "The association of selected pathological features with prostate cancer in a single-needle biopsy accession.." Hum. Pathol.. 1998 December ; 29 (12): 1536-8. Pubmed PMID: 9865844 

Li L, Ittmann MM, Ayala G, Tsai MJ, Amato RJ, Wheeler TM, Miles BJ, Kadmon D, Thompson TC "The emerging role of the PI3-K-Akt pathway in prostate cancer progression.." Prostate Cancer Prostatic Dis.. 2005 8 (2): 108-18. Pubmed PMID: 15724144 

Greene DR, Egawa S, Neerhut G, Flanagan W, Wheeler TM, Scardino PT "The distribution of residual cancer in radical prostatectomy specimens in stage A prostate cancer.." J. Urol.. 1991 February ; 145 (2): 324-8; discussi. Pubmed PMID: 1988723 

Aihara M, Scardino PT, Truong LD, Wheeler TM, Goad JR, Yang G, Thompson TC "The frequency of apoptosis correlates with the prognosis of Gleason Grade 3 adenocarcinoma of the prostate.." Cancer. 1995 January 15; 75 (2): 522-9. Pubmed PMID: 7529128 

Ohori M, Scardino PT, Lapin SL, Seale-Hawkins C, Link J, Wheeler TM "The mechanisms and prognostic significance of seminal vesicle involvement by prostate cancer.." Am. J. Surg. Pathol.. 1993 December ; 17 (12): 1252-61. Pubmed PMID: 8238732 

Ohori M, Wheeler TM, Scardino PT "The New American Joint Committee on Cancer and International Union Against Cancer TNM classification of prostate cancer. Clinicopathologic correlations.." Cancer. 1994 July 1; 74 (1): 104-14. Pubmed PMID: 7516262 

Ohori M, Wheeler TM, Dunn JK, Stamey TA, Scardino PT "The pathological features and prognosis of prostate cancer detectable with current diagnostic tests.." J. Urol.. 1994 November ; 152 (5): 1714-20. Pubmed PMID: 7523718 

Riccardi VM, Wheeler TM, Pickard LR, King B "The pathophysiology of neurofibromatosis. II. Angiosarcoma as a complication.." Cancer Genet. Cytogenet.. 1984 July ; 12 (3): 275-80. Pubmed PMID: 6426776 

Scardino PT, Frankel JM, Wheeler TM, Meacham RB, Hoffman GS, Seale C, Wilbanks JH, Easley J, Carlton CE "The prognostic significance of post-irradiation biopsy results in patients with prostatic cancer.." J. Urol.. 1986 March ; 135 (3): 510-6. Pubmed PMID: 3944896 

Ayala G, Wang D, Wulf G, Frolov A, Li R, Sowadski J, Wheeler TM, Lu KP, Bao L "The prolyl isomerase Pin1 is a novel prognostic marker in human prostate cancer.." Cancer Res.. 2003 October 1; 63 (19): 6244-51. Pubmed PMID: 14559810 

Mouraviev V, Li L, Tahir SA, Yang G, Timme TM, Goltsov A, Ren C, Satoh T, Wheeler TM, Ittmann MM, Miles BJ, Amato RJ, Kadmon D, Thompson TC "The role of caveolin-1 in androgen insensitive prostate cancer.." J. Urol.. 2002 October ; 168 (4): 1589-96. Pubmed PMID: 12352463 

Wheeler TM, Johnson EH, Coughlin D, Greenberg SD "The sensitivity of detection of asbestos bodies in sputa and bronchial washings.." Acta Cytol.. 32 (5): 647-50. Pubmed PMID: 2458660 

Egawa S, Wheeler TM, Scardino PT "The sonographic appearance of irradiated prostate cancer.." Br J Urol. 1991 August ; 68 (2): 172-7. Pubmed PMID: 1884145 

Light JK, Rapoll E, Wheeler TM "The striated urethral sphincter: muscle fibre types and distribution in the prostatic capsule.." Br J Urol. 1997 April ; 79 (4): 539-42. Pubmed PMID: 9126081 

Truong LD, Mody DR, Cagle PT, Jackson-York GL, Schwartz MR, Wheeler TM "Thymic carcinoma. A clinicopathologic study of 13 cases.." Am. J. Surg. Pathol.. 1990 February ; 14 (2): 151-66. Pubmed PMID: 1689123 

Rubenfeld S, Wheeler TM "Thyroid cancer presenting as a hot thyroid nodule: report of a case and review of the literature.." Thyroidology. 1988 April ; (1): 63-8. Pubmed PMID: 2484898 

Amrikachi M, Ponder TB, Wheeler TM, Smith D, Ramzy I "Thyroid fine-needle aspiration biopsy in children and adolescents: experience with 218 aspirates.." Diagn. Cytopathol.. 2005 April ; 32 (4): 189-92. Pubmed PMID: 15754376 

Shariat SF, Menesses-Diaz A, Kim IY, Muramoto M, Wheeler TM, Slawin KM "Tissue expression of transforming growth factor-beta1 and its receptors: correlation with pathologic features and biochemical progression in patients undergoing radical prostatectomy.." Urology. 2004 June ; 63 (6): 1191-7. Pubmed PMID: 15183988 

Ohori M, Shinohara K, Wheeler TM, Aihara M, Wessels EC, Carter SS, Scardino PT "Ultrasonic detection of non-palpable seminal vesicle invasion: a clinicopathological study.." Br J Urol. 1993 November ; 72 (5): 799-808. Pubmed PMID: 7506627 

Egawa S, Carter SS, Wheeler TM, Scardino PT "Ultrasonographic changes in the normal and malignant prostate after definitive radiotherapy.." Urol. Clin. North Am.. 1989 November ; 16 (4): 741-9. Pubmed PMID: 2683303 

Mouraviev V, Villers A, Bostwick DG, Wheeler TM, Montironi R, Polascik TJ "Understanding the pathological features of focality, grade and tumour volume of early-stage prostate cancer as a foundation for parenchyma-sparing prostate cancer therapies: active surveillance and focal targeted therapy.." BJU Int.. 2011 October ; 108 (7): 1074-85. Pubmed PMID: 21489116 

Egawa S, Wheeler TM, Greene DR, Scardino PT "Unusual hyperechoic appearance of prostate cancer on transrectal ultrasonography.." Br J Urol. 1992 February ; 69 (2): 169-74. Pubmed PMID: 1311217 

Srigley JR, Amin MB, Epstein JI, Grignon DJ, Humphrey PA, Renshaw AA, Wheeler TM "Updated protocol for the examination of specimens from patients with carcinomas of the prostate gland.." Arch. Pathol. Lab. Med.. 2006 July ; 130 (7): 936-46. Pubmed PMID: 16831046 

Eastham JA, Kattan MW, Riedel E, Begg CB, Wheeler TM, Gerigk C, Gonen M, Reuter V, Scardino PT "Variations among individual surgeons in the rate of positive surgical margins in radical prostatectomy specimens.." J. Urol.. 2003 December ; 170 (6): 2292-5. Pubmed PMID: 14634399 

Gaudin PB, Wheeler TM, Epstein JI "Verumontanum mucosal gland hyperplasia in prostatic needle biopsy specimens. A mimic of low grade prostatic adenocarcinoma.." Am. J. Clin. Pathol.. 1995 December ; 104 (6): 620-6. Pubmed PMID: 8526203 

Ramasubbu K, Wheeler TM, Reardon MJ, Dokainish H "Visceral pericardial hemangioma: unusual location for a rare cardiac tumor.." J Am Soc Echocardiogr. 2005 September ; 18 (9): 981. Pubmed PMID: 16153530 

Bova GS, Parmigiani G, Epstein JI, Wheeler T, Mucci NR, Rubin MA "Web-based tissue microarray image data analysis: initial validation testing through prostate cancer Gleason grading.." Hum. Pathol.. 2001 April ; 32 (4): 417-27. Pubmed PMID: 11331959