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Histology Test Menu
Specimen types: 10% Neutral Buffered Formalin fixed tissue, Fresh tissue in Michel's media, FFPE Tissue Block, Unstained Charged slides
Services: Technical Component, Professional Services, Global Services, and Consultations
| Test Name | Routine Histology | Special Stains | Immunohistochemistry | In-situ Hybridization | Direct Immunofluorescence |
|---|---|---|---|---|---|
| Description | Grossing, processing, embedding, sectioning and H&E staining of NBF fixed tissue | Special stains are used to differentiate some specific components that cannot be distinguished by H&E stain | IHC refers to the process of detecting antigens (e.g., proteins) in cells of a tissue section by exploiting the principle of antibodies binding specifically to antigens in biological tissues | In situ hybridization (ISH) is a type of hybridization that uses a labeled complementary DNA, RNA or modified nucleic acids strand (i.e., probe) to localize a specific DNA or RNA sequence in a portion or section of tissue (in situ) | Immunofluorescent staining of skin samples |
| Specimen Requirements | 10% Neutral Buffered Formalin fixed tissue | 10% NBF fixed tissue, FFPE block, Unstained charged slides | 10% NBF fixed tissue, FFPE block, Unstained charged slides | 10% NBF fixed tissue, FFPE block, Unstained charged slides | Skin biopsy in Michel's transport media |
| Supplies for Submission | 10% Neutral Buffered Formalin filled specimen containers | N/A | N/A | N/A | Michel's transport media filled specimen containers |
| Storage/Transport | Store specimens at room temperature (15 to 30°C), Transport ambient temperature (1°C to 55°C) | Store specimens at room temperature (15 to 30°C), Transport ambient temperature (1°C to 55°C) | Store specimens at room temperature (15 to 30°C), Transport ambient temperature (1°C to 55°C) | Store specimens at room temperature (15 to 30°C), Transport ambient temperature (1°C to 55°C) | Specimens in Michel's media stable for up to 5 days at room temperature (15 to 30°C), transport ambient temperature (1°C to 55°C) |
| Turn Around Time | 24 - 48 hours | 48 hours | 48 hours | 48 hours | 48 - 72 hours |
| Limitations | Specimens fixed or processed in alternative fixatives (alcohol, Prefer®) or heavy metal fixatives (B-4 or B-5). Frozen specimens. | Specimens fixed or processed in alternative fixatives (alcohol, Prefer®) or heavy metal fixatives (B-4 or B-5). Frozen specimens. | Specimens fixed or processed in alternative fixatives (alcohol, Prefer®) or heavy metal fixatives (B-4 or B-5). Frozen specimens. | Specimens fixed or processed in alternative fixatives (alcohol, Prefer®) or heavy metal fixatives (B-4 or B-5). Frozen specimens. | Specimens collected in 10% neutral buffered formalin cannot be stained with this procedure. |
| CPT Code(s) | 88304, 88305 | 88313 | 88342, 88341, 88344 | 88365, 88364 | 88346 X5 |
| Library | H&E | AFB AB/PAS COLLOIDAL IRON CONGO RED FERRIC IRON FITES FONTANA GIEMSA GMS GRAM MUCICARMINE PAS-FUNGAL PAS-NON FUNGAL STEINER VVG |
BCL-1 BCL-2 BCL-6 BER-EP4 CD1a CD3 CD4 CD5 CD7 CD8 CD10 CD15 CD20 CD21 CD23 CD30 CD31 CD34 CD43 CD45 CD56 CD61 CD68 CD71 CD79a CD117 CD138 CEA CHROMOGRANIN CKAE1/AE3 CK7 CK20 CK8/18 CK-HMW DESMIN E-CADHERIN EMA ERG FACTOR XIIIa HHV-8 HMB-45 HSVI/II HPYLORI LAMBDA IHC KAPPA IHC KI67 MART-1 BROWN MART-1 RED MART-1/KI67 MLH-1 MSH-2 MSH-6 MUM1 Neurofilament NKI-C3 P16 P63 P504s PAX-5 PIN4 PMS-2 PRAME S100 SMA SOX-10 BROWN SOX-10 RED SYNAPTOPHYSIN TREPONEMA PALLIDUM TTF-1 VZV |
Kappa Lambda |
IgM IgG IgA C3 Fibrinogen |
Cytology Test Menu
Specimen types: Fresh fluid specimens; FNA specimens in cytology fixative; direct smear slides; brushings collected in cytology fixative; washings fresh or collected in cytology fixative
Services: Technical Component, Professional Services, Global Services, and Consultations
| Test Name | Routine Cytology |
|---|---|
| Description | Grossing, processing |
| Specimen Requirements | Fresh tissue; specimen collected in cytology fixative; direct smear slides fixed in alcohol or air-dried completely; specimen brushings collected in cytology fixative |
| Supplies for Submission | Slides, cytology fixative |
| Storage/Transport | Store specimens at room temperature (15 to 30°C), Transport ambient temperature (1°C to 55°C) |
| Turn Around Time | 24 - 48 hours |
| Limitations | Specimens fixed or processed in alternative fixatives. |
| CPT Code(s) | 88108, 88112, 88104, 88173, 83805, 88172, 88177, 89060 |
| Library | Papanicolaou on direct smear, 88104 Papanicolaou on cytospin, 88108 FNA smear, 88173 Diff-Quik on direct smear, 88104 Diff-Quik on cytospin, 88108 Cell block, 88305 Specimen adequacy, microscope, 88172, 88177 Papanicolaou on ThinPrep slide, 88112 Crystal evaluation, 89060 |